Response to OKN-007 and NAC in a Patient with Unilateral Hearing Loss and Chronic Tinnitus from Vestibular Schwannoma Otology and Neurotology (under review)Read More
Enhanced cryoprotective effect of sucrose on the physicochemical stability of colloidal systems: a case study with siRNA-loaded poly (lactic-co-glycolic acid) nanoparticles
October 28, 2022Read More
Electrophysiological Assessment and Pharmacological Treatment of Blast-Induced Tinnitus
January 7, 2021Read More
Gene therapy for hair cell regeneration: Review and new data
July 13, 2020Read More
Cochlear hair cell regeneration: an emerging opportunity to cure noise-induced sensorineural hearing loss.
May 4, 2018Read More
Regeneration of Cochlear Hair Cells and Hearing Recovery through Hes1 Modulation with siRNA Nanoparticles in Adult Guinea Pigs
May 2, 2018Read More
HPN-07, a free radical spin trapping agent, protects against functional, cellular and electrophysiological changes in the cochlea induced by acute acoustic trauma
October 9, 2017Read More
siRNA-loaded biodegradable nanocarriers for therapeutic MAPK1 silencing against cisplatin-induced ototoxicity
October 9, 2017Read More
Antioxidants reduce neurodegeneration and accumulation of pathologic Tau proteins in the auditory system after blast exposure
May 16, 2017Read More
Ameliorative effects of antioxidants on the accumulation of hippocampal pathologic Tau variants in a rat model of blast-induced traumatic brain injury.
December 16, 2015Read More
Efficacy and safety of N-acetylcysteine in prevention of noise induced hearing loss: a randomized clinical trial
January 15, 2015Read More
Antioxidants reduce phenotypic and functional changes in the inner ear and cochlear nucleus induced by intense noise
June 15, 2014Read More
Effects of Antioxidant Treatment on Blast-Induced Brain Injury
November 5, 2013Read More
Regeneration of mammalian cochlear and vestibular hair cells through Hes1/Hes5 modulation with siRNA
March 27, 2012Read More
Magnetic targeted delivery of dexamethasone acetate across the round window membrane in guinea pigs
January 1, 2013Read More
Selective degeneration of synapses in the dorsal cochlear nucleus of chinchilla following acoustic trauma and effects of antioxidant treatment.
January 1, 2012Read More
Antioxidant treatment reduces blast-induced cochlear damage and hearing loss
March 1, 2012Read More
Incorporation, Release and Effectiveness of Dexamethasone in Biodegradable Poly (lactic-co-glycolic acid) Nanoparticles for Inner Ear Drug Delivery. Journal of Nanotechnology in Engineering and Medicine. 2(1).
February 1, 2011Read More
Reduced formation of oxidative stress biomarkers and migration of mononuclear phagocytes in the cochleae of chinchilla after antioxidant treatment in acute acoustic trauma International Journal of Otolaryngology, doi:10.1155/2011/612690 (2011)
January 1, 2011Read More
Effects of Delayed and Extended Antioxidant Treatment on Acute Acoustic Trauma. Free Radic Res. 45(10):1162-72 (2011)
May 1, 2011Read More
Dosing Study on the effectiveness of Salicylate/N-acetylcysteine for prevention of noise-induced hearing loss. Noise Health
July 1, 2010Read More
Magnetic Assisted Transport of PLGA Nanoparticles Through a Human Round Window Membrane Model
August 2, 2010Read More
Detecting incipient inner-ear damage from impulse noise with otoacoustic emissions
February 1, 2009Read More
Pharmacological approaches to the prevention and treatment of cochlear injury due to noise.
July 2, 2009Read More
American Academy of Audiology, Influence of Ultrahigh-Frequency Hearing Thresholds on Distortion-Product Otoacoustic Emission Levels at Conventional Frequencies
June 1, 2008Read More
Effectiveness of 4-OHPBN alone and in combination with other antioxidant drugs in the treatment of acute acoustic trauma in chinchilla.
February 1, 2008Read More
Magnetically-Targeted, Technetium 99m-Labeled Nanoparticles to the Inner Ear.
June 1, 2008Read More
Nitrones as Therapeutics
November 15, 2008Read More
Effectiveness of 4-hydroxy phenyl N-tert-butylnitrone (4-OHPBN) alone and in combination with other antioxidant drugs in the treatment of acute acoustic trauma in chinchilla
November 20, 2007Read More
Risk factors for distortion product otoacoustic emissions in young men with normal hearing.
October 4, 2007Read More
Distribution of PLGA nanoparticles in chinchilla cochleae.
October 1, 2007Read More
Noise protection with N-acetyl-l-cysteine (NAC) using a variety of noise exposures, NAC doses, and routes of administration.
September 1, 2007Read More
Pharmacological rescue of noise-induced hearing loss using N-acetylcysteine and acetyl-L-carnitine.
April 1, 2007Read More
Magnetic Characterization of superparamagnetic nanoparticles pulled through model membranes.
January 4, 2007Read More
Dispersion of super paramagnetic iron oxide nanoparticles in poly(d,l-lactide-co-glycolide) microparticles
January 1, 2007Read More
NAC for noise: From the bench top to the clinic.
April 24, 2006Read More
The permeability of SPION over an artificial three-layer membrane is enhanced by external magnetic field.
April 1, 2006Read More
Magnetic nanoparticles: inner ear targeted molecule delivery and middle ear implant.
January 1, 2006Read More
Efficacy of the antioxidant N-acetylcysteine (NAC) in protecting ears exposed to loud music.
April 17, 2006Read More
Prevention of impulse noise-induced hearing loss with antioxidants.
March 1, 2005Read More
Choline acetyltransferase: regulation and coupling with protein kinase and vesicular acetylcholine transporter on synaptic vesicles.
January 1, 2004Read More
Mitochondrial dysfunction in hearing loss.
September 1, 2004Read More
Transtympanic management of tinnitus.
April 2, 2003Read More
Demonstration of functional coupling between grama-aminobutyric acid (GABA) synthesis and vesicular GABA transport into synaptic vesciles.
April 1, 2003Read More
Vestibular testing abnormalities in individuals with motion sickness.
July 2, 2003Read More
Effect of trans-bullar gentamicin treatment on guinea pig angular and linear vestibulo-ocular reflexes.
October 1, 2003Read More